PAHs and Puberty in Girls at Increased Breast Cancer Risk
DESCRIPTION: Young girls start breast development at increasingly younger ages for reasons that are largely unknown. There are some data that suggest environmental chemicals may affect the start of pubertal development. We invited LEGACY girls and their mothers or guardians to complete questionnaires on growth and development and exposures to polycyclic aromatic hydrocarbons (PAHs), such as consumption of grilled or smoked foods and exposure to cigarette smoke. Other important sources of PAH exposure are air pollution. We will also measure PAH exposure in the blood and urine obtained from LEGACY girls.